Эффективные методы избавления от похмелья. Научный подход. Что делать?

Научный подход 10 апреля

 

Поэтому хотим снизить симптомы похмелья – максимально тормозим поступление алкоголя в кровь. Пьем сладкие негазированные напитки. И, конечно, светлые. Лучше водку чистоганом.

Синдром гипомагниемии, или дефицита магния, у хронических алкоголиков норма, и нарушение балланса калия и натрия [15,16,17].

 

Довольно часто ему приходиться поднимать людей после гуляний. Завтра деловая встреча, а с кровати не встать. Тут врачи ставят капельницу в вену заливают физраствор (читай «NaCl») и глюкозу. Точнее так называемый раствор Рингера. Плюс туда добавляют витамины/минералы и какие-нибудь транквилизаторы. Плюс, иногда, сердечные. Спишь крепко, бегаешь в уборную, про сушняк забываешь сразу. Спишь долго. Всё хорошо, но стоит денег. Так же врачи для борьбы с ацидозом вливают 4-процентный раствор гидрокарбоната натрия. Капельницы очень эффективны. Но не все могут себя дать прокапать. Поэтому мы просто воспроизвели капельницу, но не в вену, а в желудок.

Источники:

1. Kera Y, Ohbora Y, Komura S (1989). «Buthionine sulfoximine inhibition of glutathione biosynthesis
enhances hepatic lipid peroxidation in rats during acute ethanol intoxication». Alcohol Alcohol. 24 (6):
519-24. PMID 2576368.
2. Stickel F, Schuppan D, Hahn EG, Seitz HK (July 2002). «Cocarcinogenic effects of alcohol in
hepatocarcinogenesis». Gut 51 (1): 132-9. doi:10.1136/gut.51.1.132. PMID 12077107. PMC 1773267
3. Wiese JG, Shlipak MG, Browner WS (6 June 2000). «The alcohol hangover». Ann. Intern. Med. 132
(11): 897—902. PMID 10836917
4. Damrau F, Goldberg AH. Adsorption of whisky congeners by activated charcoal. Chemical and clinical
studies related to hangover. Southwest Med. 1971; 52.179-82
5. Pawan GL. Alcoholic drinks and hangover effects [Abstract]. Proc Nutr Soc. 1973; 32.15A
6. Damrau F, Liddy E. Hangovers and whisky congeners: comparison of whisky with vodka. Journal of
the National Medical Association. 1960; 52.262-4
7. Chapman LF. Experimental induction of hangover. Q J Stud Alcohol. 1970; 5.Suppl 567-86
8. Heikkonen E, Ylikahri R, Roine R, Valimaki M, Harkonen M, Salaspuro M. Effect of alcohol on exerciseinduced
changes in serum glucose and serum free fatty acids. Alcohol Clin Exp Res. 1998; 22.437-43.
9. Palmer JP, Ensinck JW. Stimulation of glucagon secretion by ethanol-induced hypoglycemia in man.
Diabetes. 1975; 24.295-300
10. J Forensic Leg Med. 2007 Oct;14(7):398-405. Epub 2007 May 16. Alcohol concentration and
carbonation of drinks: the effect on blood alcohol levels.
11. Alcohol Clin Exp Res. 2013 Apr;37(4):696-702. doi: 10.1111/acer.12039. Epub 2012 Dec 6. Artificial
sweeteners versus regular mixers increase breath alcohol concentrations in male and female social
drinkers.
12. Jump up to: abcYi Peng, Hong Shi, Xue-bin Qi, Chun-jie Xiao, Hua Zhong, Run-lin Z Ma, Bing Su (2010).
"The ADH1B Arg47His polymorphism in East Asian populations and expansion of rice domestication
in history". BMC Evolutionary Biology10: 15. doi:10.1186/1471-2148-10-15. PMC2823730.
PMID20089146.
13. Prat, Gemma; Adan, Ana; Sánchez-Turet, Miquel (1 June 2009). "Alcohol hangover: a critical review of
explanatory factors". Human Psychopharmacology: Clinical and Experimental 24 (4): 259–267.
14. Emerg Med Clin North Am. 1990 Nov;8(4):761-73.Electrolyte abnormalities in the alcoholic
patient.Ragland G1.
15. Alcohol Clin Exp Res. 1986 Dec;10(6):590-4.Magnesium deficiency in alcoholism. Flink EB.
16. Medicina (Kaunas). 2002;38(9):892-5.[Blood plasma potassium, sodium and magnesium levels in
chronic alcoholism during alcohol withdrawal].
17. E EFFECT OF ALCOHOL ON THE WATER AND ELECTROLYTE BALANCE IN MAN By WILLIAM M.
NICHOLSON AND HAYWOOD M. TAYLOR (From the Departments of Medicine and Biochemistry, Duke
University School of Medicine, Durham)
18. Krebs, H. A.; Freedland, R. A.; Hems, R.; Stubbs, Marion (1969-03-01). "Inhibition of hepatic
gluconeogenesis by ethanol". Biochemical Journal 112 (1): 117–124. ISSN 0264-6021
19. Emerg Med J. 2006 Jun; 23(6): 417–420.doi: 1136/emj.2004.017590 PMCID: PMC2564331 Alcoholic
ketoacidosis L C McGuire, A M Cruickshank, and P T Munro
20. PARANTAINEN, J. Prostaglandins in alcohol intolerance and hangover. Drug and Alcohol Dependence
11(3–4):239–248, 1983
21. Alcohol Hangover. Mechanisms and Mediators. Robert Swift, M.D., Ph.D.; and Dena Davidson, Ph.D.
22. http://www.bhs.umn.edu/alcohol-drugs/absorption-rate-factors.htm
23. SEPPALA, T.; LEINO, T.; LINNOILA, M.; HUTTUNEN, M.O.; AND YLIKAHRI, R.H. Effects of hangover on
psychomotor skills related to driving: Modification by fructose and glucose. Acta Pharmacologia
Toxicologia 38:209–218, 1976.
24. Ylikahri RH, Leino T, Huttunen MO, Poso AR, Eriksson CJ, Nikkila. Effects of fructose and glucose on
ethanol-induced metabolic changes and on the intensity of alcohol intoxication and hangover. Eur J. Clin Invest. 1976; 6.93-10
25. Am J Physiol. 1982 Jun;242(6):F586-91.Systemic effects of NaHCO3 in experimental lactic acidosis
in dogs. Arieff AI, Leach W, Park R, Lazarowitz VC.
26. Rohsenow, DJ; Howland, J (June 2010). "The role of beverage congeners in hangover and other
residual effects of alcohol intoxication: a review". Current drug abuse reviews 3 (2): 76–9.
doi:10.2174/1874473711003020076. PMID 20712591.
27. Pittler, MH; Verster, JC; Ernst, E (Dec 24, 2005). "Interventions for preventing or treating alcohol
hangover: systematic review of randomized controlled trials". BMJ (Clinical research ed.) 331 (7531):
1515–8. doi:10.1136/bmj.331.7531.1515. PMC 1322250. PMID 16373736.
28. GIRRE, C.; HISPARD, E.; PALOMBO, S.; N’GUYEN,C.; AND DALLY, S. Increased metabolism of
acetaminophen in chronically alcoholic patients. Alcoholism: Clinical & Experimental Research 17(1):
170–173, 1993.
29. J Perinatol. 2015 Aug;35(8):601-6. doi: 10.1038/jp.2015.37. Epub 2015 Apr 30.Effects of sodium
bicarbonate correction of metabolic acidosis on regional tissue oxygenation in very low birth weight
neonates.
30. Kaivola, S., et al. "Hangover headache and prostaglandins: prophylactic treatment with tolfenamic
acid." Cephalalgia 3.1 (1983): 31-36.
31. Moesgaard S, Hansen NV. GLA effectively reduces hangovers. Pharma Nord Research, unpublished
report.
32. Laas I. A double-blind placebo-controlled study on the effects of Morning Fit on hangover symptoms
after a high level of alcohol consumption in healthy volunteers. J Clin Res 1999;2: 9-15
33. Gopi, Sreeraj, et al. "Studies on the effectiveness, safety and tolerability of two doses of Anti Hangover
Drink in Reducing Alcohol Induced Hangover Symptoms in Adult Male Social Drinkers."
Int.J.Cur.Res.Aca.Rev. 2.8 (2014): 125-131.
34. Manu, M. B., and S. A. Kolhapure. "Evaluation of the Efficacy and Safety of “PartySmart” in the
Prevention of Alcohol-induced Hangover: A Prospective, Randomized, Double Blind, Comparative,
Phase III Clinical Trial." INDIAN JOURNAL OF CLINICAL PRACTICE 15.7 (2004).
35. Pittler MH, Verster JC, Ernst E. Interventions for preventing or treating alcohol hangover: systematic
review of randomised controlled trials. BMJ. 2005 Dec 24;331(7531):1515-8.
36. Khan MA, Jensen K, Krogh HJ. Alcohol-induced hangover. A double-blind comparison of pyritinol and
placebo in preventing hangover symptoms. Q J Stud Alcohol. 1973; 34.1195-201
37. Maxwell, CR; Spangenberg, RJ; Hoek, JB; Silberstein, SD; Oshinsky, ML (Dec 31, 2010). "Acetate
causes alcohol hangover headache in rats.". PLoS ONE 5 (12): e15963.
doi:10.1371/journal.pone.0015963. PMC 3013144. PMID 21209842.
38. ReviewEffects of mixing alcohol with caffeinated beverages on subjective intoxication: A systematic
review and meta-analysis. Sarah Bensona, Joris C. Verstera, b, Chris Alfordc, Andrew Scholeya.

Поделиться
Отправить
Опубликовал Артем Волков

Авторизация

Авторизовавшись, вы сможете задать интересующий вас вопрос или приобрести товары в интернет–магазине.